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原发性无分泌型浆细胞白血病:多发性骨髓瘤的一种罕见变异型。

Primary nonsecretory plasma cell leukemia: a rare variant of multiple myeloma.

作者信息

Kawada E, Shinonome S, Saitoh T, Tamura J, Karasawa M, Sawamura M, Murakami H

机构信息

Department of Internal Medicine, Fujioka General Hospital, Gunma, Japan.

出版信息

Ann Hematol. 1999 Jan;78(1):25-7. doi: 10.1007/s002770050467.

DOI:10.1007/s002770050467
PMID:10037265
Abstract

We report a patient with primary nonsecretory plasma cell leukemia. These cells resembled prolymphocytes and expressed only CD38 and CD56. Due to the atypical morphology and lack of monoclonal immunoglobulins in both serum and urine, it was difficult to make a correct diagnosis. Electron-microscopic and immunocytochemical cytoplasmic studies were useful.

摘要

我们报告了一例原发性非分泌型浆细胞白血病患者。这些细胞类似于幼淋巴细胞,仅表达CD38和CD56。由于其非典型形态以及血清和尿液中均缺乏单克隆免疫球蛋白,因此难以做出正确诊断。电子显微镜检查和免疫细胞化学细胞质研究很有帮助。

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引用本文的文献

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Oligosecretory Primary Plasma Cell Leukemia with Atypical Morphological Abnormality.伴有非典型形态异常的寡分泌性原发性浆细胞白血病
Intern Med. 2019 Aug 1;58(15):2213-2217. doi: 10.2169/internalmedicine.2472-18. Epub 2019 Apr 17.
2
Primary non-secretory plasma cell leukemia with atypical morphology - a case report.原发性非分泌型浆细胞白血病伴非典型形态学表现——1例报告
Indian J Hematol Blood Transfus. 2009 Jun;25(2):81-3. doi: 10.1007/s12288-009-0019-1. Epub 2009 Jul 5.
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Nonsecretory primary plasma cell leukemia with good response to thalidomide-based treatment.
Int J Hematol. 2007 Jul;86(1):66-8. doi: 10.1532/IJH97.E0617.