Plummer D J, Banker A, Taskintuna I, Azen S P, Sample P A, LaBree L, Freeman W R
Shiley Eye Center, Department of Ophthalmology, School of Medicine, University of California San Diego, La Jolla 92093-0946, USA.
Arch Ophthalmol. 1999 Feb;117(2):202-7. doi: 10.1001/archopht.117.2.202.
To determine the sensitivity and specificity of entoptic perimetry as a noninvasive test for detecting retinal damage due to peripheral cytomegalovirus (CMV) retinitis.
A masked study comparing entoptic perimetry with fundus photography under 4 experimental conditions (determined by increasing pixel sizes) on 2 separate testing sessions.
Acquired immunodeficiency syndrome Ocular Research Unit at the University of California, San Diego.
Twenty-four human immunodeficiency virus-positive and 8 human immunodeficiency virus-negative subjects; 21 eyes with documented CMV retinitis, and 26 eyes that were retinitis free.
For each testing session, screening method, and condition, the presence of CMV retinitis was determined for each meridian (i.e., clock hour), each quadrant (consisting of 3 meridians), and each eye (consisting of all meridians); the amount of retinitis was defined as the percentage of meridians or quadrants with CMV retinitis.
Entoptic perimetry was as sensitive and specific as fundus photography in determining the presence of CMV retinitis. Determination of the amount of CMV retinitis tended to be underestimated by perimetry for larger pixel sizes.
Entoptic perimetry may be an effective and inexpensive alternative to fundus photography for CMV retinitis in hospitals and community clinics.
确定视内视野检查作为一种无创检测方法用于检测外周巨细胞病毒（CMV）视网膜炎所致视网膜损伤的敏感性和特异性。
一项在2个独立测试环节中，于4种实验条件下（由增大像素尺寸确定）对视内视野检查与眼底照相进行比较的双盲研究。
加利福尼亚大学圣地亚哥分校获得性免疫缺陷综合征眼科研究室。
24例人类免疫缺陷病毒阳性和8例人类免疫缺陷病毒阴性受试者；21只眼睛有CMV视网膜炎记录，26只眼睛无视网膜炎。
对于每个测试环节、筛查方法和条件，确定每个子午线（即时钟小时）、每个象限（由3个子午线组成）以及每只眼睛（由所有子午线组成）是否存在CMV视网膜炎；视网膜炎的程度定义为有CMV视网膜炎的子午线或象限的百分比。
在确定CMV视网膜炎的存在方面，视内视野检查与眼底照相一样敏感和特异。对于较大像素尺寸，视内视野检查往往会低估CMV视网膜炎的程度。
对视内视野检查可能是医院和社区诊所中用于CMV视网膜炎检测的一种有效且廉价的替代眼底照相的方法。
