Károlyi Z, Erös N, Kriston R
Miskolc Város Onkormányzat Semmelweis Kórház-Rendelöintézet Börgyógyászati Osztály.
Orv Hetil. 1999 Jan 24;140(4):191-4.
Strongyloidiasis is a parasitic disease, caused by Strongyloides stercoralis, an intestinal nematode, which is mainly endemic in tropical and subtropical regions. It can be sporadically found in the temperate zone, especially in closed communities and among people living under bad social conditions. Gastrointestinal, pulmonary and cutaneous symptoms may arise during the migration of the larvae. The infections are chronic and poor in symptoms among immunocompetent patients. Sometimes the cutaneous manifestation is the only symptom of the disease besides the distinct eosinophilia. Intense itching, erythematosus papule and petechiae develop at the site of the skin infection. Rapidly progressing linear, serpiginous, urticarial streaks are the pathognomic cutaneous manifestations that are called larva currents. The appearance of erythematosus, linear stripes are due to the migrating larvae in the skin. The most common nonspecific symptoms are urticaria, maculopapular exanthema, localized or generalized pruritus and prurigo. The parasite is uniquely able to carry out its whole life cycle inside the human body, so in immunocompromised patients the disease can lead to a hyperinfection syndrome with high mortality, due to the accelerated endogenous autoinfection. Authors present all possible skin manifestations of the strongyloidiasis, based on the case history of three brothers and sisters and that of a female patient suffering from hyperinfection syndrome.
类圆线虫病是一种由肠道线虫粪类圆线虫引起的寄生虫病，主要流行于热带和亚热带地区。在温带地区也可偶尔发现，尤其是在封闭社区以及生活在恶劣社会条件下的人群中。幼虫移行过程中可能出现胃肠道、肺部和皮肤症状。免疫功能正常的患者感染通常为慢性且症状不明显。有时除明显的嗜酸性粒细胞增多外，皮肤表现是该病的唯一症状。皮肤感染部位会出现剧烈瘙痒、红斑丘疹和瘀点。迅速进展的线状、匐行性、荨麻疹样条纹是具有诊断意义的皮肤表现，称为幼虫移行症。红斑、线状条纹的出现是由于幼虫在皮肤内移行所致。最常见的非特异性症状是荨麻疹、斑丘疹、局部或全身性瘙痒及痒疹。这种寄生虫能够在人体内存完成整个生命周期，因此在免疫功能低下的患者中，由于内源性自身感染加速，该病可导致高死亡率的超感染综合征。作者根据三兄妹以及一名患有超感染综合征的女性患者的病史，介绍了类圆线虫病所有可能的皮肤表现。
