钬钇铝石榴石激光辐射对脑膜瘤和神经鞘瘤的光消融作用。
Photoablation of meningiomas and neurinomas by Holmium Yag laser radiation.
作者信息
Leyser S, König H J, Foth H J, Meyer D
机构信息
Department of Neurosurgery, Westpfalz-Klinikum GmbH, Kaiserslautern, Germany.
出版信息
Neurol Res. 1999 Jan;21(1):96-8. doi: 10.1080/01616412.1999.11740901.
Cranial rat bone was irradiated by 2.1 microns Holmium Yag laser radiation. Quantitative edge rates were calculated. Histologic sections were investigated by light and electron microscopy. Eighteen cases of hard fibrous or calcified spinal and cranial meningiomas and neurinomas were operated upon using pulsed laser beam. In rat cranial bone ablation rate ranged between 0.3-0.5 mm per pulse. Perifocal thermal damage was observed in a zone of 20-90 microns around the lesion. In all human cases tumors could be removed totally without additional neurological deficit. In vivo heat development was measured by an i.r.-camera.
用波长2.1微米的钬钇铝石榴石激光辐射大鼠颅骨。计算定量边缘率。通过光学显微镜和电子显微镜对组织学切片进行研究。使用脉冲激光束对18例硬纤维性或钙化性脊髓和颅骨脑膜瘤及神经鞘瘤进行手术。大鼠颅骨的消融率为每脉冲0.3 - 0.5毫米。在病变周围20 - 90微米的区域观察到灶周热损伤。在所有人类病例中，肿瘤均可完全切除，且无额外的神经功能缺损。通过红外摄像机测量体内发热情况。
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