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孢子丝菌性脑膜炎

Sporothrix meningitis.

作者信息

Wescott B L, Nasser A, Jarolim D R

机构信息

VA Medical Center, Muskogee, Okla., USA.

出版信息

Nurse Pract. 1999 Feb;24(2):90, 93-4, 97-8 passim.

Abstract

Sporothrix schenckii is a fungus commonly found in soil and on plants, wood splinters, rosebush thorns, and decaying vegetation. It is also carried by some wild and domestic animals and rodents. When this organism penetrates the skin of individuals handling contaminated substances, the cutaneous manifestation may be lymphangitic or fixed. The treatment of choice for the cutaneous form of the disease (sporotrichosis) is potassium iodide. If iodides are contraindicated or not tolerated, itraconazole may be used. Sporotrichosis can persist for years if unrecognized and can progress to systemic forms, including osteoarticular, pulmonary (may occur when the organism is inhaled), and meningeal involvement. Systemic forms can be life-threatening and very difficult to treat. Primary care providers must be familiar with this disorder and its presentation because it is easily mistaken for a bacterial infection and inappropriately treated.

摘要

申克孢子丝菌是一种常见于土壤、植物、木片、玫瑰丛刺和腐烂植被中的真菌。它也存在于一些野生动物、家畜和啮齿动物身上。当这种病原体侵入接触受污染物质的个体皮肤时,皮肤表现可能为淋巴管型或固定型。皮肤型疾病(孢子丝菌病)的首选治疗方法是碘化钾。如果禁忌使用或不能耐受碘化物,则可使用伊曲康唑。如果未被识别,孢子丝菌病可能会持续数年,并可能发展为全身型,包括骨关节型、肺部型(当病原体被吸入时可能发生)和脑膜型。全身型可能危及生命且治疗非常困难。初级保健提供者必须熟悉这种疾病及其表现,因为它很容易被误诊为细菌感染并接受不恰当的治疗。

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