Cioli S, D'Arrigo V
Ophthalmologica. 1976;173(6):505-12. doi: 10.1159/000307936.
With circular chromatography on paper, we have tested the content of the free amino acids in the normal and cataractous bovine and human lens capsule and lens. The interpretation of the data shows that the normal bovine lens without capsule presents a greater quantity of free amino acids in relation to the bovine cataractous lens without capsule; the lens capsule of normal bovine lens presents a lesser quantity of free amino acids in relation to the lens capsule of the bovine cataractous lens; the normal human lens without capsule presents a relative increase in quantity of free amino acids in relation to the cataractous human lens without capsule (cortical and nuclear cataract); the lens capsule of the normal human lens presents a decrease in the quantity of free amino acids in relation to the lens capsule of the cataractous human lens (cortical and nuclear cataract); the human cataractous lens in "cataracta nigra" presents a marked decrease in quantity of free amino acids in relation to cataractous human lens without capsule (nuclear and cortical cataract), while the lens capsule of "cataracta nigra", presents a marked increase in quantity of free amino acids in relation to the normal human lens capsule, and decrease in relation to the lens capsule of the cataractous human lens (cortical and nuclear cataract).
通过纸环色谱法,我们检测了正常及患白内障的牛和人晶状体囊膜及晶状体中游离氨基酸的含量。数据解读表明,无囊膜的正常牛晶状体相较于无囊膜的患白内障牛晶状体含有更多的游离氨基酸;正常牛晶状体的囊膜相较于患白内障牛晶状体的囊膜含有较少的游离氨基酸;无囊膜的正常人类晶状体相较于无囊膜的患白内障人类晶状体(皮质性和核性白内障)游离氨基酸数量相对增加;正常人类晶状体的囊膜相较于患白内障人类晶状体(皮质性和核性白内障)的囊膜游离氨基酸数量减少;“黑色白内障”中的患白内障人类晶状体相较于无囊膜的患白内障人类晶状体(核性和皮质性白内障)游离氨基酸数量显著减少,而“黑色白内障”的囊膜相较于正常人类晶状体囊膜游离氨基酸数量显著增加,相较于患白内障人类晶状体(皮质性和核性白内障)的囊膜则减少。