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根据核心温度和平均皮肤温度预测寒颤产热。

Prediction of shivering heat production from core and mean skin temperatures.

作者信息

Tikuisis P, Giesbrecht G G

机构信息

Defence and Civil Institute of Environmental Medicine, Toronto, Ontario, Canada.

出版信息

Eur J Appl Physiol Occup Physiol. 1999 Feb;79(3):221-9. doi: 10.1007/s004210050499.

Abstract

Prediction formulae of shivering metabolism (Mshiv) are critical to the development of models of thermoregulation for cold exposure, especially when the extrapolation of survival times is required. Many such formulae, however, have been calibrated with data that are limited in their range of core temperatures (Tc), seldom involving values of less than 36 degrees C. Certain recent studies of cold-water immersion have reported Tc as low as 33.25 degrees C. These data comprise measurements of Tc (esophageal) and mean skin temperature (Ts), and metabolism from 14 males [mean (SD); age = 28 (5) years; height = 1.78 (0.06) m; body mass = 77.7 (6.9) kg; body fat (BF) = 18.4 (4.5)%] during immersion in water as cold as 8 degrees C for up to 1 h and subsequent self-rewarming via shivering under dry blanketed conditions. The data contain 3343 observations with mean (SD) Tc and Ts of 35.92 (0.93) degrees C and 23.4 (8.9) degrees C, respectively, and have been used to re-examine the prediction of Mshiv. Rates of changes of these temperatures were not used in the analysis. The best fit of the formulae, which are essentially algebraic constructs with and without setpoints, are those with a quadratic expression involving Ts. This is consistent with the findings of Benzinger (1969) who demonstrated that the thermosensitivity of skin is parabolic downwards with temperature peaking near a value of 20 degrees C. Formulae that included a multiplicative interaction term between Tc and Ts did not predict as well. The best prediction using 37 degrees C and 33 degrees C as the Tc and Ts setpoints, respectively, was found with BF as an attenuation factor: Mshiv (W x m(-2)) = [155.5 x (37- Tc) + 47.0 x (33 - Ts) - 1.57 x (33 - Ts)2]/(%BF)(0.5).

摘要

寒战代谢(Mshiv)的预测公式对于冷暴露体温调节模型的开发至关重要,尤其是在需要外推生存时间的情况下。然而,许多这样的公式是根据核心温度(Tc)范围有限的数据校准的,很少涉及低于36摄氏度的值。最近关于冷水浸泡的某些研究报告的Tc低至33.25摄氏度。这些数据包括14名男性[平均(标准差);年龄 = 28(5)岁;身高 = 1.78(0.06)米;体重 = 77.7(6.9)千克;体脂(BF) = 18.4(4.5)%]在8摄氏度的冷水中浸泡长达1小时以及随后在干燥毛毯条件下通过寒战自行复温期间的Tc(食管)、平均皮肤温度(Ts)和代谢测量值。数据包含3343次观测,平均(标准差)Tc和Ts分别为35.92(0.93)摄氏度和23.4(8.9)摄氏度,并已用于重新检验Mshiv的预测。分析中未使用这些温度的变化率。这些公式本质上是有和没有设定点的代数结构,最佳拟合公式是那些包含涉及Ts的二次表达式的公式。这与本津格(1969年)的研究结果一致,他证明皮肤的热敏感性随温度呈抛物线下降,在接近20摄氏度的值时达到峰值。包含Tc和Ts之间乘法相互作用项的公式预测效果不佳。分别以37摄氏度和33摄氏度作为Tc和Ts的设定点,以BF作为衰减因子时发现最佳预测公式为:Mshiv(瓦×米⁻²) = [155.5×(37 - Tc) + 47.0×(33 - Ts) - 1.57×(33 - Ts)²]/(%BF)⁰·⁵ 。

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