Robinson N J, Marindo R
INSERM Unit 88, Hôpital National de Saint-Maurice, France.
J Acquir Immune Defic Syndr Hum Retrovirol. 1999 Feb 1;20(2):187-94. doi: 10.1097/00042560-199902010-00012.
Estimates of HIV prevalence in 1995 among all adults in Zimbabwe range between about 18% and 24%. The objective of this study was to estimate, for Zimbabwe, the impact of HIV infection on adult mortality, by age and gender, between 1995 and the year 2000.
For this analysis, we used 1992 census data to estimate the number of non-HIV-related deaths, and a short-term projection model to estimate the number of deaths attributed to HIV infection in 1995 and the year 2000.
It was estimated that between 52% and 60% of all adult deaths in 1995 were attributed to HIV infection, and between 69% and 76% in both males and females in the group between 20 and 39 years of age. The estimated adult mortality rate per 1000 increased from 9.8 in 1987 (based on census data) to between 20.6 and 24.3 in 1995. For the year 2000, it was projected that between 66% and 73% of all adult deaths would be attributed to HIV infection, and between 81% and 86% in those aged 20 to 39 years. The estimated adult mortality rate in the year 2000 increased to between 29.1/1000 and 36.6/1000. Even if all transmission was assumed to cease after 1995, it was projected that >60% of adult deaths would be attributed to HIV in the year 2000. Adult population growth is projected to decrease to between 0.3% and 1.0% in the year 2000.
Results suggest that the impact of HIV infection on mortality in Zimbabwe is already severe and will continue to increase. Efforts to reduce numbers of new HIV infections today will serve to reduce the future burden of mortality, particularly in the longer term.
1995年津巴布韦所有成年人中艾滋病毒感染率估计在18%至24%之间。本研究的目的是估计1995年至2000年期间艾滋病毒感染对津巴布韦成年人死亡率按年龄和性别的影响。
为进行此项分析,我们使用1992年人口普查数据估计与艾滋病毒无关的死亡人数,并使用短期预测模型估计1995年和2000年归因于艾滋病毒感染的死亡人数。
据估计,1995年所有成年人死亡中52%至60%归因于艾滋病毒感染,20至39岁年龄组中男性和女性的这一比例在69%至76%之间。每1000名成年人的估计死亡率从1987年的9.8(基于人口普查数据)增至1995年的20.6至24.3。对于2000年,预计所有成年人死亡中66%至73%将归因于艾滋病毒感染,20至39岁年龄组的这一比例在81%至86%之间。2000年估计的成年人死亡率增至每1000人29.1至36.6。即使假设1995年后所有传播均停止,预计2000年仍有超过60%的成年人死亡将归因于艾滋病毒。预计2000年成年人口增长率将降至0.3%至1.0%之间。
结果表明,艾滋病毒感染对津巴布韦死亡率的影响已经很严重,而且还将继续增加。如今减少新的艾滋病毒感染人数的努力将有助于减轻未来的死亡负担,特别是从长期来看。