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Comparative in vitro activities of amoxicillin-clavulanate against aerobic and anaerobic bacteria isolated from antral puncture specimens from patients with sinusitis.阿莫西林-克拉维酸对从鼻窦炎患者上颌窦穿刺标本中分离出的需氧菌和厌氧菌的体外比较活性。
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4
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Antimicrob Agents Chemother. 2003 Jun;47(6):1963-7. doi: 10.1128/AAC.47.6.1963-1967.2003.
5
In vitro activities of ABT-773, a new ketolide, against aerobic and anaerobic pathogens isolated from antral sinus puncture specimens from patients with sinusitis.新型酮内酯类药物ABT-773对从鼻窦炎患者上颌窦穿刺标本中分离出的需氧和厌氧病原体的体外活性。
Antimicrob Agents Chemother. 2001 Aug;45(8):2363-7. doi: 10.1128/AAC.45.8.2363-2367.2001.

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Surveillance of antimicrobial resistance in Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis in the United States in 1996-1997 respiratory season. The Laboratory Investigator Group.1996 - 1997年呼吸道疾病流行季节美国肺炎链球菌、流感嗜血杆菌和卡他莫拉菌耐药性监测。实验室研究小组。
Diagn Microbiol Infect Dis. 1997 Dec;29(4):249-57. doi: 10.1016/s0732-8893(97)00195-8.
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Gram-positive anaerobic cocci.革兰氏阳性厌氧球菌
Clin Microbiol Rev. 1998 Jan;11(1):81-120. doi: 10.1128/CMR.11.1.81.
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Antimicrobial resistance in anaerobes.厌氧菌中的抗菌药物耐药性。
Clin Infect Dis. 1997 Jan;24 Suppl 1:S110-20. doi: 10.1093/clinids/24.supplement_1.s110.
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Microbiology of the transition from acute to chronic maxillary sinusitis.从急性上颌窦炎转变为慢性上颌窦炎的微生物学
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5
Comparison of Etest to broth microdilution method for testing Streptococcus pneumoniae susceptibility to levofloxacin and three macrolides.Etest法与肉汤微量稀释法检测肺炎链球菌对左氧氟沙星和三种大环内酯类药物敏感性的比较。
Antimicrob Agents Chemother. 1996 Oct;40(10):2413-5. doi: 10.1128/AAC.40.10.2413.
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Antimicrobial resistance of Streptococcus pneumoniae recovered from outpatients in the United States during the winter months of 1994 to 1995: results of a 30-center national surveillance study.1994年至1995年冬季美国门诊患者中分离出的肺炎链球菌的耐药性：一项30中心全国监测研究的结果
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Bacteriology and beta-lactamase activity in acute and chronic maxillary sinusitis.急慢性上颌窦炎的细菌学及β-内酰胺酶活性
Arch Otolaryngol Head Neck Surg. 1996 Apr;122(4):418-22; discussion 423. doi: 10.1001/archotol.1996.01890160058011.
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Effect of carbon dioxide on in vitro susceptibility of anaerobic bacteria to erythromycin.二氧化碳对厌氧菌体外对红霉素敏感性的影响。
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Effect of carbon dioxide on erythromycin.二氧化碳对红霉素的影响。
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阿莫西林-克拉维酸对从鼻窦炎患者上颌窦穿刺标本中分离出的需氧菌和厌氧菌的体外比较活性。

Comparative in vitro activities of amoxicillin-clavulanate against aerobic and anaerobic bacteria isolated from antral puncture specimens from patients with sinusitis.

作者信息

Goldstein E J, Citron D M, Merriam C V

机构信息

R. M. Alden Research Laboratory, Santa Monica-UCLA Medical Center, Santa Monica, California 90404, USA.

出版信息

Antimicrob Agents Chemother. 1999 Mar;43(3):705-7. doi: 10.1128/AAC.43.3.705.

DOI:10.1128/AAC.43.3.705
PMID:10049296
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC89189/
Abstract

By an agar dilution method, the antimicrobial susceptibilities of antral sinus puncture isolates were studied. Pneumococci were generally susceptible to amoxicillin, azithromycin, and clarithromycin, but 17% of pneumococcal isolates were resistant to cefuroxime. Haemophilus influenzae isolates were resistant to amoxicillin and clarithromycin. beta-Lactamase production occurred in 69% of Prevotella species. One-third of Peptostreptococcus magnus isolates were resistant to azithromycin and clarithromycin. Cefuroxime had limited activity against Prevotella species and P. magnus. Levofloxacin was active against most isolates except peptostreptococci. Amoxicillin-clavulanate was active against all isolates, with the MIC at which 90% of the isolates were inhibited being < or = 1 microgram/ml.

摘要

采用琼脂稀释法研究了鼻窦穿刺分离株的抗菌药敏情况。肺炎球菌通常对阿莫西林、阿奇霉素和克拉霉素敏感，但17%的肺炎球菌分离株对头孢呋辛耐药。流感嗜血杆菌分离株对阿莫西林和克拉霉素耐药。69%的普雷沃菌属产生β-内酰胺酶。三分之一的大消化链球菌分离株对阿奇霉素和克拉霉素耐药。头孢呋辛对普雷沃菌属和大消化链球菌的活性有限。左氧氟沙星对除消化链球菌外的大多数分离株有活性。阿莫西林-克拉维酸对所有分离株均有活性，90%分离株被抑制的最低抑菌浓度≤1微克/毫升。