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美国肝硬化死亡率与酒精消费的生态学研究

An ecologic study of cirrhosis mortality and alcohol consumption in the U.S.

作者信息

Gasiorowicz M, Remington P

机构信息

UW-Madison Department of Professional Development and Applied Studies 53701-2659, USA.

出版信息

WMJ. 1999 Jan-Feb;98(1):48-51.

PMID:10050155
Abstract

Liver cirrhosis is responsible for 350 deaths in Wisconsin each year. A number of ecologic studies indicate that alcohol consumption and cirrhosis mortality are highly correlated. This ecologic cross-sectional study uses data for the 50 US states. Various measures of alcohol consumption and Hepatitis B and C serve as the exposure variables. Liver cirrhosis mortality is the outcome measure. Wisconsin has the largest percentage of drinkers and of binge drinkers and is in the top five states for apparent per capita alcohol consumption and for the percentage of chronic heavy drinkers. Yet Wisconsin's mortality rate during 1990 to 1994 ranks 43 among US states. The most plausible explanation for this apparent anomaly is that alcohol consumption in Wisconsin is distributed over a larger share of the population. Overall, consumption per drinker in Wisconsin is lower than in other high consumption states.

摘要

肝硬化每年在威斯康星州导致350人死亡。多项生态学研究表明,酒精消费与肝硬化死亡率高度相关。这项生态学横断面研究使用了美国50个州的数据。酒精消费以及乙型和丙型肝炎的各种衡量指标作为暴露变量。肝硬化死亡率作为结果指标。威斯康星州饮酒者和酗酒者的比例最高,在人均酒精表观消费量和慢性重度饮酒者比例方面位列美国前五个州。然而,威斯康星州在1990年至1994年期间的死亡率在美国各州中排名第43位。对这一明显异常现象最合理的解释是,威斯康星州的酒精消费分布在更大比例的人口中。总体而言,威斯康星州每个饮酒者的消费量低于其他高消费州。

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