Badalamente M A, Hurst L C
Department of Orthopaedics, Health Science Center, State University of New York at Stony Brook, USA.
Hand Clin. 1999 Feb;15(1):35-42, v-vi.
The molecular biochemical aspects of Dupuytren's disease have been studied for decades. This article summarizes biochemical influences on myofibroblast contractility, endogenous and exogenous chemical regulation, the influence of growth factors, and the biochemistry of collagen. A clear insight into the biochemistry of Dupuytren's disease may provide a foundation for future clinical interventions.
几十年来,人们一直在研究掌腱膜挛缩症的分子生化方面。本文总结了对肌成纤维细胞收缩性的生化影响、内源性和外源性化学调节、生长因子的影响以及胶原蛋白的生物化学。对掌腱膜挛缩症生物化学的清晰洞察可能为未来的临床干预提供基础。