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[紫杉醇治疗过程中发生心房颤动的非小细胞肺癌患者]

[Atrial fibrillation in a patient with non-small-cell carcinoma of the lung in the course of paclitaxel therapy].

作者信息

Moscetti L, Ramponi S, Maccaglia C, Villanti P, Cortesi E

机构信息

Dipartimento di Medicina Sperimentale, Università La Sapienza, Italia.

出版信息

Clin Ter. 1998 Sep-Oct;149(5):377-9.

PMID:10052252
Abstract

We report a clinical case of a patient with NSCLC who experienced an atrial fibrillation during paclitaxel infusion. Before chemotherapy, his cardiological function was normal. No cardiovascular and/or thyroid associated disease were previously reported. The patient did not receive any drugs with pro-arrhythmic effects. Incidence of cardiovascular toxicity in patients treated with paclitaxel is low, and does not justify strict cardiological monitoring otherwise deserved to patients with preexistent risk factors.

摘要

我们报告了1例非小细胞肺癌患者在紫杉醇输注过程中发生心房颤动的临床病例。化疗前，其心脏功能正常。既往未报告有心血管和/或甲状腺相关疾病。该患者未接受任何具有促心律失常作用的药物。接受紫杉醇治疗的患者发生心血管毒性的发生率较低，对于无既往危险因素的患者而言，并不需要进行严格的心脏监测。

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引用本文的文献

1
Atrial fibrillation following treatment with paclitaxel: A case report.紫杉醇治疗后发生心房颤动：一例报告。
Biomed Rep. 2018 Dec;9(6):540-544. doi: 10.3892/br.2018.1158. Epub 2018 Oct 12.