Vinck B M, Van Cauwenberge P B, Leroy L, Corthals P
University Hospital Ghent, Department of Otorhinolaryngology, University of Ghent, Postgraduate Institute of Speech Therapy and Audiology, Belgium.
Audiology. 1999 Jan-Feb;38(1):44-52. doi: 10.3109/00206099909073001.
Measurement of otoacoustic emissions (OAEs) has been proposed as a sensitive test to reliably assess the effects of noise exposure. The present study in humans was designed to evaluate the sensitivity and applicability of transient evoked OAEs (TEOAEs) and 2f1-f2 distortion product OAEs (DPOAEs) as quantitative indices of the functional integrity of the outer hair cells (OHC) during growth of and recovery from temporary threshold shift (TTS). This was examined in two different groups of volunteers by measuring the per- and post-stimulatory effects of a one hour BBN and an on-site five hour exposure to loud music from a discotheque. The results of both experiments show consistent growth and recovery patterns for both DPOAEs and TEOAEs. For TEOAEs, both the reproducibility scores and signal to noise ratio values for the 4 kHz frequency band exhibited the greatest sensitivity. The DPOAEs, on the other hand, showed the greatest sensitivity between 2 and 5.5 kHz. Thus, both the TEOAEs and DPOAEs have a great potential in the detection of TTS after noise exposure.
耳声发射（OAEs）测量已被提议作为一种敏感测试，用于可靠评估噪声暴露的影响。本项人体研究旨在评估瞬态诱发耳声发射（TEOAEs）和2f1-f2畸变产物耳声发射（DPOAEs）作为临时阈移（TTS）发生及恢复过程中外毛细胞（OHC）功能完整性定量指标的敏感性和适用性。通过测量两组不同志愿者在一小时BBN刺激前后以及在现场暴露于迪斯科舞厅嘈杂音乐五小时前后的情况来进行此项研究。两个实验的结果均显示DPOAEs和TEOAEs具有一致的增长和恢复模式。对于TEOAEs，4 kHz频段的再现性得分和信噪比数值表现出最大的敏感性。另一方面，DPOAEs在2至5.5 kHz之间表现出最大的敏感性。因此，TEOAEs和DPOAEs在检测噪声暴露后的TTS方面都具有巨大潜力。
