Lhermitte F, Dérouesné J
Rev Neurol (Paris). 1976 Oct;132(10):669-80.
Twenty-five patients with "amnesic aphasia" were studied. The language difficulty is not related either to intellectual deficit, generalised memory disturbance or visual impairment but is a specific verbal memory defect. Amnesic aphasia also involves lack of perception of linguistic units which is caused by impairment of comprehension and erasure of the acoustico-mnesic traces of words. The responsible lesions are in the left temporal region. The authors maintain that, from the physio-pathological point of view, these lesions do not destroy the cortex and sub-cortex, as in focal necrosis, but cause cortical dysfunction selectively affecting the mnesic traces of words.
对25例“遗忘性失语症”患者进行了研究。语言障碍与智力缺陷、全身性记忆障碍或视力损害均无关,而是一种特定的言语记忆缺陷。遗忘性失语症还涉及对语言单位的感知缺失,这是由理解受损和单词的听觉记忆痕迹消除所导致的。责任病灶位于左侧颞叶区域。作者认为,从生理病理学角度来看,这些病灶不像局灶性坏死那样破坏皮质和皮质下结构,而是选择性地导致皮质功能障碍,影响单词的记忆痕迹。