Sipponen P, Saukkonen M, Varis K, Siurala M
Acta Hepatogastroenterol (Stuttg). 1979 Dec;26(6):493-8.
Relative chief and parietal cell volume densities were estimated morphometrically in the remnant mucosa of 98 male patients ("series"), operated on for duodenal ulcer by the Billroth II, and in the body mucosa of 55 subjects, age and sex matched, from a random series of a Finnish population ("controls"). The relative volumes of chief and parietal cells were significantly lower in the series than in the controls. The mean chief cell: parietal cell ratio was significantly higher in the series than in the controls. In the controls the ratio decreased with increasing loss of normal tubules. However, no such decrease was discernable in the series, owing to wide scatter of the individual ratios. High ratios (greater than or equal 2.0) were found in 17 cases of the series and in one of the controls. These 17 patients with high ratios had a significantly higher mean length of the foveoles and a significantly lower mean score of the round cell infiltration than the operated patients with lower ratios.
对98例因十二指肠溃疡接受毕罗Ⅱ式手术的男性患者（“系列病例”）的残余黏膜以及55例年龄和性别匹配的芬兰人群随机系列（“对照组”）的胃体黏膜进行形态计量学评估，以估算主细胞和壁细胞的相对体积密度。系列病例中主细胞和壁细胞的相对体积显著低于对照组。系列病例中主细胞与壁细胞的平均比例显著高于对照组。在对照组中，该比例随正常小管丧失的增加而降低。然而，在系列病例中未观察到这种降低，因为个体比例的离散度较大。系列病例中有17例以及对照组中有1例的比例较高（大于或等于2.0）。这17例比例较高的患者的小凹平均长度显著更长，圆形细胞浸润的平均评分显著低于比例较低的手术患者。
