Egli A, Gruber U F
Schweiz Med Wochenschr. 1976 Sep 18;106(38):1268-72.
Six prospective, randomized studies using intermittent pneumatic compression of the calf for prevention of postoperative deep vein thrombosis are available and have been analyzed. In 4 studies a significant reduction in the incidence of deep vein thrombosis could be demonstrated. Compared to controls, the reduction in the deep vein thrombosis rate by intermittent compression is about 60%. The frequency of deep vein thrombosis is lower if the patients are treated not only intraoperatively but also for 24-28 h postoperatively. The difference in deep vein thrombosis rate between these two schedules is statistically probable significant. No definite statement can be made regarding the efficacy of deep vein thrombosis prevention in patients with malignant disease, since here the results are controversial. No studies are available on the effect of intermittent pneumatic compression of the leg on the incidence of fatal postoperative pulmonary emboli. This method must therefore be regarded as an interesting alternative in clinical investigation.