Bachmann F, McKenna R, Meredith P, Carta S
Schweiz Med Wochenschr. 1976 Dec 11;106(50):1819-21.
In a prospective study, 54 patients undergoing joint-replacement operations were randomized into a control and a treatment group. In the treatment group low pressure intermittent compression (Phlebo-Dynastat) to calves and thighs was started on the day of operation and continued until patients were fully mobilized. In 34 evaluable patients undergoing total hip arthroplasty the incidence of deep vein thrombosis (DVT) as determined by venography was 43% in the control group and 22% in the treatment group (p = 0.18). In 17 patients undergoing total knee replacement, DVT occurred postoperatively in 70% of the control group but in none of the treatment group (p = 0.002). The difference between the control and Phlebo-Dynastat group when comparing all patients was highly significant (p less than 0.005). Low pressure intermittent venous compression offers a welcome alternative method of thrombosis prophylaxis in patients with increased risk of bleeding.
在一项前瞻性研究中,54例行关节置换手术的患者被随机分为对照组和治疗组。治疗组在手术当天开始对小腿和大腿进行低压间歇性压迫(静脉动力仪),并持续至患者完全活动自如。在34例行全髋关节置换术的可评估患者中,通过静脉造影确定的对照组深静脉血栓形成(DVT)发生率为43%,治疗组为22%(p = 0.18)。在17例行全膝关节置换术的患者中,对照组70%术后发生DVT,而治疗组无一例发生(p = 0.002)。比较所有患者时,对照组和静脉动力仪组之间的差异具有高度显著性(p < 0.005)。低压间歇性静脉压迫为出血风险增加的患者提供了一种受欢迎的血栓预防替代方法。