Pervulov S, Draganić M, Todorić M, Kostić J, Rusović S, Ilić R
Vojnosanit Pregl. 1998 Nov-Dec;55(6):591-4.
Thrombosis of left atrium is frequent in the patients with mitral defect. Systemic embolism that generates by separated thrombus parts is a possible complication during the disease. Echocardiography is routinely used in the diagnosis of left atrial thrombosis. On the basis of angiographic experience, we have set the hypothesis: coronary angiography has a great sensitivity, but small specificity in the diagnosis of left atrial thrombosis. The presence of thrombus in left atrium was analyzed in 60 operated patients with mitral valve disease. During the surgery, thrombus was found in 13, and not found in 47 patients. Coronary angiography was preoperatively performed in all patients. In 9 out of 13 patients with intraoperatively observed left atrial thrombus, thrombus was also found by angiography. In 47 patients thrombus was found neither intraoperatively, and in 45 nor by angiography. The sensitivity of angiography in the diagnosis of left atrial thrombosis is 69%, specificity is 97%, and the accuracy is 90%. Positive index of anticipation is 81%, and negative index of anticipation is 91%.
二尖瓣缺损患者左心房血栓形成很常见。分离的血栓部分所引发的全身栓塞是该病可能出现的并发症。超声心动图常用于诊断左心房血栓形成。基于血管造影经验,我们提出了一个假设:冠状动脉造影在诊断左心房血栓形成方面具有较高的敏感性,但特异性较低。对60例接受二尖瓣手术的患者分析其左心房血栓情况。手术过程中,13例发现有血栓,47例未发现血栓。所有患者术前均进行了冠状动脉造影。术中观察到左心房血栓的13例患者中,9例血管造影也发现了血栓。47例患者术中未发现血栓,血管造影也未在其中45例发现血栓。血管造影诊断左心房血栓形成的敏感性为69%,特异性为97%,准确性为90%。阳性预测指数为81%,阴性预测指数为91%。