Richter K, Winzer K J, Frohberg H D, Guski H, Prihoda H, Schmitt H J, Hamm B
Institut für Röntgendiagnostik, Charité, Humboldt Universität zu Berlin.
Zentralbl Chir. 1998;123 Suppl 5:37-41.
A new technique for breast imaging is presented. This technique combines radiographic mammography directly with automated ultrasound. The combined examination, which is performed without decompression of the breast, yields the conventional mammography films as well as a complete set of B-mode scans and ultrasound projections. These can be geometrically matched with each other in a definitive manner. A prototype of the device was first used in a pilot study of 50 patients followed by a study of an additional 450 patients with a total of 492 breast lesions, of which 269 were confirmed by histology or cytology. The results show that X-ray and ultrasound are complementary in the detection of cancer. The use of an experimental mode of image interpretation for combined mammography and automated ultrasound reduced the number of mammographically suspicious findings that ultimately turned out to be benign. These results were also confirmed in two blind studies including a total of 160 histologically or cytologically confirmed lesions and 40 cases without lesions. With further technical advancement of the technique aimed at rapid and easy application and confirmation of the results obtained so far, the combination of mammography and automated ultrasound might be introduced into a routine clinical setting.
介绍了一种用于乳腺成像的新技术。该技术将乳腺X线摄影直接与自动超声相结合。这种联合检查无需对乳房进行减压，可生成传统的乳腺X线摄影胶片以及一套完整的B超扫描和超声投影图像。这些图像可以在几何上进行精确匹配。该设备的原型首先在50名患者的初步研究中使用，随后又对另外450名患者进行了研究，共发现492个乳腺病变，其中269个经组织学或细胞学证实。结果表明，X线和超声在癌症检测中具有互补性。采用联合乳腺X线摄影和自动超声的实验性图像解读模式，减少了最终被证明为良性的乳腺X线摄影可疑发现的数量。在两项包括160个经组织学或细胞学证实的病变和40个无病变病例的盲法研究中也证实了这些结果。随着该技术的进一步技术进步，旨在实现快速、简便的应用并确认迄今获得的结果，乳腺X线摄影和自动超声的联合应用可能会被引入常规临床实践。
