Gokcil Z, Odabasi Z, Demirkaya S, Eroglu E, Vural O
Department of Neurology, Gulhane Medical School, Ankara, Turkey.
J Neurol Sci. 1999 Jan 1;162(1):62-4. doi: 10.1016/s0022-510x(98)00302-5.
We report eight patients with adult-onset subacute sclerosing panencephalitis (SSPE), of which, four were treated with oral isoprinosine and four with intraventricular alpha-interferon plus oral isoprinosine. One of the four patients treated with oral isoprinosine died within two months, and the disease progressed in three patients. Of the four patients treated with oral isoprinosine plus intraventricular alpha-interferon, one showed mild progression, one remission, and the remaining two showed stabilization. The group of patients is relatively small, but our results suggest that treatment with oral isoprinosine plus alpha-interferon is effective for SSPE.
我们报告了8例成人起病的亚急性硬化性全脑炎（SSPE）患者，其中4例接受口服异丙肌苷治疗，4例接受脑室内α干扰素联合口服异丙肌苷治疗。接受口服异丙肌苷治疗的4例患者中，1例在两个月内死亡，3例病情进展。在接受口服异丙肌苷加脑室内α干扰素治疗的4例患者中，1例病情轻度进展，1例缓解，其余2例病情稳定。患者组相对较小，但我们的结果表明，口服异丙肌苷加α干扰素治疗对SSPE有效。
