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川崎病

Kawasaki syndrome.

作者信息

Mason W H, Takahashi M

机构信息

Department of Pediatrics, University of Southern California School of Medicine, and Childrens Hospital Los Angeles, 90027, USA.

出版信息

Clin Infect Dis. 1999 Feb;28(2):169-85; quiz 186-7. doi: 10.1086/515133.

DOI:10.1086/515133
PMID:10064222
Abstract

KS is a fascinating illness of childhood that has emerged over the last 30 years and is now recognized as the most common cause of acquired heart disease in children in the United States. It has a dramatic clinical presentation in most cases, but for a small number of cases that present with a more subtle disease there appears to be a greater risk of coronary artery complications. Progress has been made in the management of KS, but although the disease appears to be related to an infectious etiology, no infectious agent has been proven to be the cause. Finally, issues in long-term management and prognosis are yet to be clarified.

摘要

川崎病是一种在过去30年中出现的、引人关注的儿童疾病,目前被认为是美国儿童获得性心脏病的最常见病因。在大多数情况下,它有显著的临床表现,但对于少数表现为病情较为隐匿的病例,冠状动脉并发症的风险似乎更高。川崎病的治疗已取得进展,尽管该疾病似乎与感染病因有关,但尚未证实有感染因子是其病因。最后,长期管理和预后方面的问题仍有待阐明。

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Mercury promotes catecholamines which potentiate mercurial autoimmunity and vasodilation: implications for inositol 1,4,5-triphosphate 3-kinase C susceptibility in kawasaki syndrome.
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Kawasaki disease: 40 years after the original report.川崎病:首次报告40年后
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