Rice A M, Rivkees S A
Section of Pediatric Endocrinology, Department of Pediatrics, Yale University Medical School, New Haven, Connecticut 06520, USA.
J Pediatr. 1999 Mar;134(3):349-51. doi: 10.1016/s0022-3476(99)70462-2.
Subcutaneous fat necrosis of the newborn (SCFN) is characterized by indurated violet skin nodules and, occasionally, life-threatening hypercalcemia. Current treatments of patients with SCFN-related hypercalcemia are often only partially successful and may be associated with prolonged hypercalcemia. We now report the use of etidronate, a bisphosphonate, to control hypercalcemia in an infant with SCFN.
新生儿皮下脂肪坏死（SCFN）的特征是皮肤出现硬结性紫色结节，偶尔还会出现危及生命的高钙血症。目前，针对与SCFN相关的高钙血症患者的治疗往往仅取得部分成功，且可能伴有高钙血症持续时间延长的情况。我们现在报告使用双膦酸盐依替膦酸来控制一名患有SCFN的婴儿的高钙血症。
