Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Section of Pediatric Dermatology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Pediatr Dermatol. 2021 Jul;38(4):982-983. doi: 10.1111/pde.14664. Epub 2021 Jun 18.
Subcutaneous fat necrosis (SCFN) is an inflammatory disorder of the adipose tissue that commonly presents in neonates as tender subcutaneous nodules on the trunk and extremities with hypercalcemia as a potential complication. We report the case of a 3-month-old female who presented with circular alopecia of the scalp and was found to have histopathologically confirmed SCFN. Recognition of SCFN as a cause for alopecia in young infants may allow prompt screening for hypercalcemia and reduce the risk for associated morbidity and mortality.
皮下脂肪坏死症(SCFN)是一种脂肪组织的炎症性疾病,常见于新生儿,表现为躯干和四肢有触痛的皮下结节,其潜在并发症为高钙血症。我们报告了一例 3 月龄女性,其头皮出现圆形脱发,组织病理学证实为 SCFN。认识到 SCFN 是幼儿脱发的原因,可以及时筛查高钙血症,降低相关发病率和死亡率。