Bass E M, Shaff M I
S Afr Med J. 1976 Nov 27;50(51):2041-3.
A clear distinction between obstructive and hepatocellular jaundice is difficult in many patients. Biochemical and clinical findings may cause confusion and result in long delays in diagnosis and treatment. Ultrasonography is a major advance in the positive identification of patients with dilated intrahepatic ducts, whether or not the gall bladder is dilated. Isotopic imaging also may be useful in identifying obstructive jaundice. If percutaneous transhepatic cholangiography (PTC) is performed soon after, the site and nature of the obstruction will become evident. Another advance is the introduction of a sheathless narrow needle for PTC. This reduces the possibility of complications and has the advantage of being able to puncture a normal, undilated biliary tree in as many as 60% of cases, ruling out an obstructive cause. The use of these newer radiological investigations will appreciably shorten the period between the onset of jaundice and the ascertainment of its cause.
对许多患者而言,很难明确区分梗阻性黄疸和肝细胞性黄疸。生化检查结果和临床症状可能会造成混淆,导致诊断和治疗延误很久。超声检查在明确肝内胆管扩张患者(无论胆囊是否扩张)方面是一项重大进展。同位素成像在识别梗阻性黄疸方面也可能有用。如果在此之后不久进行经皮肝穿刺胆管造影(PTC),梗阻的部位和性质将变得清晰可见。另一项进展是引入了用于PTC的无鞘细针。这降低了并发症的可能性,并且具有能够在多达60%的病例中穿刺正常、未扩张胆管树的优势,从而排除梗阻性病因。使用这些更新的放射学检查方法将显著缩短黄疸出现至明确病因之间的时间。