Mazor M, Furman B, Bashiri A
Department of Obstetrics and Gynecology, Soroka Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Gynecol Endocrinol. 1998 Dec;12(6):421-7. doi: 10.3109/09513599809012845.
We have proposed a model in which the initiation of human parturition in the presence of infection is mediated by the host response. Systemic infections such as pyelonephritis, or localized intrauterine maternal infections such as deciduitis and cervicitis, might trigger parturition via the monocyte/macrophage system in both maternal blood and human decidua. According to this model, labor is to be considered an event that occurs when the intrauterine or maternal environment is hostile to the well-being of the fetus, as was supported by recent studies. From this point of view, the initiation of preterm labor may have survival value.
我们提出了一个模型，即在存在感染的情况下，人类分娩的启动是由宿主反应介导的。全身性感染如肾盂肾炎，或局部性宫内母体感染如蜕膜炎和宫颈炎，可能通过母体血液和人类蜕膜中的单核细胞/巨噬细胞系统触发分娩。根据这个模型，分娩被认为是当宫内或母体环境对胎儿的健康不利时发生的事件，这一观点得到了最近研究的支持。从这个角度来看，早产的启动可能具有生存价值。
