Lundgren S, Rasmusson L, Sjöström M, Sennerby L
Department of Oral and Maxillofacial Surgery, Umeå University, Sweden.
Int J Oral Maxillofac Surg. 1999 Feb;28(1):31-7.
The aim of the present study was to histologically analyse the bone graft-titanium implant interface after six and twelve months of healing for a simultaneous approach and after six months for a delayed approach. For this purpose, screw-shaped c.p. titanium microimplants, 2 mm in diameter and 5 mm long, were placed and retrieved at different time intervals in ten consecutive patients with severely resorbed maxillae and treated with iliac cortico-cancellous bone grafts and titanium implants in a two-stage procedure. The histomorphometrical analyses of ground sections of the specimens showed a higher degree of bone-implant contact and more bone filling the implant threads in the delayed approach microimplants. This was probably due to the partly revascularized grafted bone in the delayed approach being able to respond to the surgical trauma, resulting in interfacial bone formation. It is concluded that the results from the present study favour the use of a delayed approach when using free autogenous bone grafts and titanium implants for reconstruction of the severely atrophied maxilla.
本研究的目的是对同期植入法愈合6个月和12个月后以及延期植入法愈合6个月后的骨移植-钛种植体界面进行组织学分析。为此，在10例连续的严重上颌骨吸收患者中，采用两阶段手术，植入直径2 mm、长5 mm的螺纹型纯钛微种植体，并在不同时间间隔取出。对标本磨片进行组织形态计量学分析显示，延期植入法的微种植体骨-种植体接触程度更高，种植体螺纹内填充的骨更多。这可能是由于延期植入法中部分再血管化的移植骨能够对手术创伤做出反应，从而导致界面骨形成。得出的结论是，本研究结果支持在使用游离自体骨移植和钛种植体重建严重萎缩的上颌骨时采用延期植入法。
