Kreiborg S, Cohen M M
Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen, Denmark.
Acta Odontol Scand. 1998 Dec;56(6):339-41. doi: 10.1080/000163598428275.
This article reviews previous research on the craniofacial development in Apert and Crouzon syndromes and adds new roentgencephalometric information. It is concluded that craniofacial development in the two syndromes is not the same. Marked differences were found in the calvaria, cranial base, orbit, maxilla, zygoma, incisal occlusion, and soft tissue profile. In general, abnormal craniofacial morphology was more severe in Apert syndrome than in Crouzon syndrome.
本文回顾了以往关于Apert综合征和Crouzon综合征颅面发育的研究，并补充了新的X线头影测量信息。得出的结论是，这两种综合征的颅面发育并不相同。在颅骨、颅底、眼眶、上颌骨、颧骨、切牙咬合和软组织侧貌方面发现了明显差异。一般来说，Apert综合征的异常颅面形态比Crouzon综合征更严重。
