Takeuchi S, Hirano H, Ichio T, Taniguchi H, Toyoda N
Department of Obstetrics and Gynecology, Mie University School of Medicine, Japan.
J Obstet Gynaecol Res. 1999 Feb;25(1):29-32. doi: 10.1111/j.1447-0756.1999.tb01118.x.
Carcinomas other than adenocarcinomas are extremely rare in the fallopian tube. A 42-year-old woman with watery, intermittent vaginal discharge was found to have a left adnexal tumor. This case was diagnosed as primary carcinoma of the fallopian tube, FIGO Stage Ia. She underwent a total abdominal hysterectomy, a bilateral salpingo-oophorectomy, a pelvic and periaortic lymphoadenectomy, and an omentectomy, followed by cisplatin-based chemotherapy. Four years after the initial diagnosis of the disease, she remains in a disease-free state. Histologically, the tumor revealed a primary transitional cell carcinoma of the left fallopian tube. The findings on an immunohistochemical test for an epithelial membrane antigen, the CA125 antigen, were positive, whereas findings on a test for CEA were negative. We report a case of a malignant neoplasm of the fallopian tube with histological features of transitional cell carcinoma that arose from the tubal epithelium.
除腺癌外,输卵管癌极为罕见。一名42岁女性,有水性、间歇性阴道分泌物,被发现有左侧附件肿瘤。该病例被诊断为原发性输卵管癌,国际妇产科联盟(FIGO)Ia期。她接受了全腹子宫切除术、双侧输卵管卵巢切除术、盆腔和腹主动脉旁淋巴结清扫术以及大网膜切除术,随后进行了以顺铂为基础的化疗。在疾病最初诊断四年后,她仍处于无病状态。组织学检查显示,肿瘤为左侧输卵管原发性移行细胞癌。上皮膜抗原、CA125抗原的免疫组化检测结果为阳性,而癌胚抗原(CEA)检测结果为阴性。我们报告一例具有移行细胞癌组织学特征的输卵管恶性肿瘤病例,该肿瘤起源于输卵管上皮。