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[原发性输卵管癌。1例报告并文献复习]

[Primary fallopian tube carcinoma. Report of a single case with review of the literature].

作者信息

Friedrich M, Villena-Heinsen C, Bonkhoff H, Schmidt W

机构信息

Universitätsfrauenklinik und Poliklinik mit Hebammenlehranstalt Homburg/Saar, Deutschland.

出版信息

Gynakol Geburtshilfliche Rundsch. 1997;37(4):216-20. doi: 10.1159/000272857.

Abstract

With an incidence of 0.1-1.0% of all genital malignancies, primary fallopian tube carcinoma is an extremely uncommon neoplasm of the female genital tract. We report a 58-year-old postmenopausal woman with primary fallopian tube carcinoma confined to the right fallopian tube in primary stage pT2a pN0 G3 M0, who is alive without evidence of disease 2 years after abdominal hysterectomy, bilateral adnexectomy, omentectomy and lymphonodectomy followed by an adjuvant cisplatin (70 mg/m2) and treosulfan (5 g/m2) chemotherapy. An accompanying literature review indicates that clinical signs and symptoms of fallopian tube neoplasms are usually nonspecific and include lower abdominal pain. The primary treatment remains surgical resection followed by adjuvant chemotherapy or radiation. Prognosis is poor, although long-term survivors have been reported.

摘要

原发性输卵管癌占所有女性生殖系统恶性肿瘤的0.1 - 1.0%,是一种极为罕见的女性生殖道肿瘤。我们报告一例58岁绝经后女性,患有局限于右侧输卵管的原发性输卵管癌,处于pT2a pN0 G3 M0 Ⅰ期。该患者在接受腹式子宫切除术、双侧附件切除术、大网膜切除术及淋巴结清扫术后,接受了顺铂(70 mg/m²)和苏消安(5 g/m²)辅助化疗,术后2年仍存活且无疾病迹象。一项相关文献综述表明,输卵管肿瘤的临床症状和体征通常无特异性,包括下腹部疼痛。主要治疗方法仍是手术切除,随后进行辅助化疗或放疗。尽管有长期存活者的报道,但预后较差。

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