Zhuk E A, Galenok V A
Ter Arkh. 1998;70(12):46-9.
The study of activity of T-effector lymphocytes of delayed-type hypersensitivity (DTH) in insulin-dependent diabetes (IDD) and effects of short-action insulins produced by different pharmaceutical firms.
79 IDD patients aged 3-48 entered the study.
T-effector lymphocytes activity in DTH patients was abnormal: leukocytes migration was enhanced due to inhibited production of the inhibiting factor. Effector function was subnormal. Short-acting insulins promoted normalization of the above indices. The insulins of different producers is individual in efficacy for each patient.
In vitro tests are necessary for each patient to determine insulin activity before insulin therapy.
研究胰岛素依赖型糖尿病（IDD）中迟发型超敏反应（DTH）的T效应淋巴细胞活性以及不同制药公司生产的短效胰岛素的作用。
79名年龄在3至48岁的IDD患者进入该研究。
DTH患者的T效应淋巴细胞活性异常：由于抑制因子产生受抑制，白细胞迁移增强。效应功能低于正常水平。短效胰岛素促使上述指标恢复正常。不同生产商的胰岛素对每位患者的疗效具有个体差异。
在胰岛素治疗前，对每位患者进行体外测试以确定胰岛素活性是必要的。
