Green B L, McBride B W, Sandals D, Leslie K E, Bagg R, Dick P
Department of Animal and Poultry Science, University of Guelph, ON, Canada.
J Dairy Sci. 1999 Feb;82(2):333-42. doi: 10.3168/jds.S0022-0302(99)75240-9.
An experiment was designed to examine subclinical ketosis in periparturient dairy cows and the antiketogenic effects of monensin. Subclinical ketosis was induced through a 10% feed restriction and was quantitatively determined using a blood beta-hydroxybutyrate (BHBA) threshold of 1200 mumol/L. Monensin decreased the BHBA concentration by 35% and increased the glucose concentration by 15%. No effect of monensin on milk production was detected, but rumen fermentation was altered. Monensin decreased the acetate to propionate ratio, decreased the butyrate concentration, and increased pH. The lower concentration of BHBA in blood and higher concentration of blood glucose in cows treated with a monensin controlled-release capsule decreased subclinical ketosis in early lactation cows.
设计了一项实验来检测围产期奶牛的亚临床酮病以及莫能菌素的抗酮生成作用。通过10%的饲料限制诱导亚临床酮病，并使用1200 μmol/L的血液β-羟基丁酸（BHBA）阈值进行定量测定。莫能菌素使BHBA浓度降低了35%，使葡萄糖浓度提高了15%。未检测到莫能菌素对产奶量有影响，但瘤胃发酵发生了改变。莫能菌素降低了乙酸与丙酸的比例，降低了丁酸浓度，并提高了pH值。用莫能菌素控释胶囊处理的奶牛血液中较低的BHBA浓度和较高的血糖浓度降低了早期泌乳奶牛的亚临床酮病。
