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经迷路部分切除术联合岩尖切除术治疗岩斜区肿瘤性及血管性病变的手术入路

Partial labyrinthectomy petrous apicectomy approach to neoplastic and vascular lesions of the petroclival area.

作者信息

Sekhar L N, Schessel D A, Bucur S D, Raso J L, Wright D C

机构信息

Department of Neurological Surgery, George Washington University Medical Center, Washington, District of Columbia 20037, USA.

出版信息

Neurosurgery. 1999 Mar;44(3):537-50; discussion 550-2. doi: 10.1097/00006123-199903000-00060.

Abstract

OBJECTIVE

To study the value of an improvement of the presigmoid petrosal approach to the petroclival area by the addition of partial labyrinthectomy and petrous apicectomy and to document hearing and other results.

METHODS

Thirty-six consecutive patients treated by this technique during a 2-year period were studied prospectively. The lesions treated included 33 petroclival neoplasms (25 meningiomas, 5 chordomas, 1 chondrosarcoma, 1 trigeminal schwannoma, and 1 epidermoid cyst) and 3 vertebrobasilar aneurysms. The patients underwent clinical, radiological, and neuro-otological examinations.

RESULTS

There was no perioperative mortality. Cranial nerve deficits involving Cranial Nerves III, IV, V, and VI occurred in 17 patients (47%) postoperatively. Cerebrospinal fluid leak occurred in 12 patients (33%). Four of these patients were treated by lumbar drainage, two patients were treated by lumboperitoneal shunt, and six patients required reoperation and repacking of the middle ear. Hydrocephalus occurred in five patients (13.9%). There was one case of meningitis and another of systemic sepsis. All 36 patients underwent postoperative audiometric evaluation. When serviceable hearing was present preoperatively (Gardner-Robertson Grades I or II), it was determined to be preserved at postoperative follow-up in 81% of the patients (26 of 32 patients).

CONCLUSION

The partial labyrinthectomy petrous apicectomy approach provided improved access to neoplasms of the clivus and petrous apex and the posterior cavernous sinus area and to vertebrobasilar aneurysms in the midclival area. This improvement in access permits more controlled and thorough treatment of these lesions, with reduced brain retraction and acceptable morbidity with respect to auditory function.

摘要

目的

通过增加部分迷路切除术和岩尖切除术来研究改良乙状窦前岩骨入路至岩斜区的价值,并记录听力及其他结果。

方法

前瞻性研究了在2年期间内连续接受该技术治疗的36例患者。治疗的病变包括33例岩斜区肿瘤(25例脑膜瘤、5例脊索瘤、1例软骨肉瘤、1例三叉神经鞘瘤和1例表皮样囊肿)和3例椎基底动脉瘤。患者接受了临床、影像学和神经耳科学检查。

结果

无围手术期死亡。术后17例患者(47%)出现涉及动眼神经、滑车神经、三叉神经和展神经的颅神经功能缺损。12例患者(33%)发生脑脊液漏。其中4例患者接受了腰大池引流治疗,2例患者接受了腰大池腹腔分流治疗,6例患者需要再次手术并重新填塞中耳。5例患者(13.9%)发生脑积水。发生1例脑膜炎和1例全身性脓毒症。所有36例患者均接受了术后听力测定评估。术前存在有用听力(Gardner-Robertson分级I或II级)的患者中,81%(32例中的26例)在术后随访时听力得以保留。

结论

部分迷路切除岩尖切除术入路改善了对斜坡、岩尖及海绵窦后区肿瘤以及斜坡中部椎基底动脉瘤的显露。这种显露的改善使得对这些病变的治疗更可控、更彻底,减少了脑牵拉,且听觉功能方面的发病率可接受。

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