Muckle R P, De la Cruz A, Lo W M
House Ear Clinic and House Ear Institute, Los Angeles, California 90057-9927, USA.
Am J Otol. 1998 Mar;19(2):219-25.
The accurate diagnosis of different petrous apex lesions is increasingly common as a result of modern imaging techniques, combining computed tomography and magnetic resonance imaging. The clinical features, diagnostic evaluation, imaging, and treatment outcomes of patients with petrous apex lesions are reviewed.
Retrospective case review.
Private practice tertiary otologic referral center.
Sixty-six patients treated at the House Ear Clinic in the last 2 decades for a lesion of the petrous apex. Lesions included cholesterol granuloma, cholesteatoma, and chondrosarcoma, among others. Mean follow-up time was 27 months and ranged from 1 month to 10 years.
INTERVENTION(S): Cholesterol granulomas were treated with drainage procedures, solid tumors were surgically removed using primarily the middle fossa or infratemporal fossa approaches.
The most common presenting symptoms were hearing loss, dizziness, headaches, and tinnitus. Decreased cranial nerve V function was present in 22%. The most common cystic lesion was cholesterol granuloma, which constituted 60% of all lesions in the study, followed by cholesteatoma (9%). Chondrosarcomas were the most common solid lesion (6% of all lesions). Asymmetric pneumatization and retained secretions give radiographic findings commonly overdiagnosed as lesions of the petrous apex.
Lesions of the petrous apex can be diagnosed accurately by CT and MRI and can be divided into cystic and solid lesions. Cholesterol granulomas are by far the most common lesion found in this site and can be drained with minimal morbidity via the infracochlear approach. Solid tumors may require extensive exposure and a combined skull base approach for complete removal.
由于现代成像技术(计算机断层扫描和磁共振成像相结合)的应用,不同岩尖病变的准确诊断日益常见。本文回顾了岩尖病变患者的临床特征、诊断评估、影像学表现及治疗结果。
回顾性病例分析。
私立三级耳科转诊中心。
过去20年在豪斯耳科诊所接受治疗的66例岩尖病变患者。病变包括胆固醇肉芽肿、胆脂瘤和软骨肉瘤等。平均随访时间为27个月,范围从1个月到10年。
胆固醇肉芽肿采用引流手术治疗,实体瘤主要通过中颅窝或颞下窝入路手术切除。
最常见的症状为听力减退、头晕、头痛和耳鸣。22%的患者存在颅神经V功能减退。最常见的囊性病变为胆固醇肉芽肿,占本研究所有病变的60%,其次为胆脂瘤(9%)。软骨肉瘤是最常见的实体病变(占所有病变的6%)。不对称气化和分泌物潴留的影像学表现常被过度诊断为岩尖病变。
岩尖病变可通过CT和MRI准确诊断,并可分为囊性和实体性病变。胆固醇肉芽肿是该部位迄今为止最常见的病变,可通过耳蜗下入路引流,发病率极低。实体瘤可能需要广泛暴露并采用联合颅底入路才能完全切除。