Ungar W J, Coyte P C, Chapman K R, MacKeigan L
Department of Health Administration and Division of Respirology, University of Toronto, Toronto, Canada.
Can Respir J. 1998 Nov-Dec;5(6):463-71. doi: 10.1155/1998/362797.
To assess the annual cost of asthma per adult patient from the perspectives of society, the Ontario Ministry of Health and the patient.
Prospective cost of illness evaluation.
Ambulatory out-patients residing in southern central Ontario.
Nine hundred and forty patients with asthma over 15 years of age studied between May 1995 and April 1996.
Direct costs, such as respiratory-related visits to general/family practitioners, respiratory specialists, emergency rooms, hospital admissions, laboratory tests, prescription medications, dispensing fees, devices and out-of-pocket expenses, were calculated. Indirect costs, such as absences from work or usual activities, and travel and waiting time, were studied.
Unadjusted annual costs were $2,550 per patient. Hospitalizations and medications each accounted for 22% of the total cost and indirect costs 50% of the total costs. More severe disease, older age, smoking, drug plan availability and retirement were significant predictors of costs. Annual costs per patient varied from $1,255 (95% CI $1,061 to $1,485) in young nonsmokers with no drug plan and mild disease to $5,032 (95% CI $4,347 to $5,825) in older smokers with drug plans and severe disease. Clinically important reductions in the quality of life occurred with increasing severity.
Interventions aimed at reducing productivity losses, admissions to hospital and medication costs may result in savings to society, the provincial government and the patient. The quality of policy and allocation decisions may be enhanced by cost of illness estimates that are comprehensive, precise and incorporate multiple perspectives.
从社会、安大略省卫生部和患者的角度评估成年哮喘患者的年度费用。
前瞻性疾病成本评估。
安大略省中南部的门诊患者。
1995年5月至1996年4月期间研究的940名15岁以上的哮喘患者。
计算直接成本,如与呼吸相关的看全科医生/家庭医生、呼吸专科医生、急诊室、住院、实验室检查、处方药、配药费、器械和自付费用。研究间接成本,如缺勤或无法进行日常活动、出行和等待时间。
未经调整的每位患者年度费用为2550美元。住院和药物费用各占总成本的22%,间接成本占总成本的50%。病情更严重、年龄较大、吸烟、是否有药物保险计划和退休是成本的重要预测因素。每位患者的年度费用从无药物保险计划且病情较轻的年轻非吸烟者的1255美元(95%可信区间为1061美元至1485美元)到有药物保险计划且病情严重的老年吸烟者的5032美元(95%可信区间为4347美元至5825美元)不等。随着病情加重,生活质量出现具有临床意义的下降。
旨在减少生产力损失、住院和药物成本的干预措施可能会为社会、省政府和患者节省开支。全面、精确且纳入多个视角的疾病成本估计可能会提高政策和资源分配决策的质量。