De Simone R, Glombitza G, Vahl C F, Albers J, Meinzer H P, Hagl S
Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany.
J Am Soc Echocardiogr. 1999 Mar;12(3):173-85. doi: 10.1016/s0894-7317(99)70133-1.
Color Doppler echocardiography does not provide adequate information about the severity of mitral regurgitation in patients with eccentric mitral regurgitation. We have developed a new procedure for 3-dimensional (3D) color Doppler reconstruction and for segmentation of regurgitant jets. The volume of regurgitant jets was compared with jet area in 63 patients with mitral regurgitation. Mitral regurgitation was assessed by angiography, regurgitant fraction and volume by pulsed Doppler, JA by planimetry, and JV by 3-dimensional Doppler. Twenty-eight patients with central jets were compared with 35 patients with eccentric jets. In the patients with eccentric jets, JV showed significant correlations with regurgitant volume (r = 0.90; P <.01) and regurgitant fraction (r = 0.76; P < .01) and was able to separate groups with different degrees of mitral regurgitation (P <.01). Three-dimensional Doppler revealed origin, direction, and spatial spreading of complex jet geometry. JV, a new parameter of mitral regurgitation, was also capable of quantifying asymmetrical jets.
彩色多普勒超声心动图无法为偏心性二尖瓣反流患者的二尖瓣反流严重程度提供足够信息。我们开发了一种用于三维（3D）彩色多普勒重建和反流束分割的新方法。在63例二尖瓣反流患者中，将反流束体积与反流束面积进行了比较。通过血管造影评估二尖瓣反流，通过脉冲多普勒评估反流分数和体积，通过平面测量法评估反流束面积（JA），通过三维多普勒评估反流束体积（JV）。将28例中心性反流束患者与35例偏心性反流束患者进行比较。在偏心性反流束患者中，JV与反流体积（r = 0.90；P <.01）和反流分数（r = 0.76；P <.01）显著相关，并且能够区分不同程度二尖瓣反流的组（P <.01）。三维多普勒揭示了复杂反流束几何形状的起源、方向和空间扩展。JV作为二尖瓣反流的一个新参数，也能够对不对称反流束进行量化。
