三维彩色多普勒：二尖瓣反流患者的临床研究。

Three-dimensional color Doppler: a clinical study in patients with mitral regurgitation.

作者信息

De Simone R, Glombitza G, Vahl C F, Albers J, Meinzer H P, Hagl S

机构信息

University of Heidelberg, Germany.

出版信息

J Am Coll Cardiol. 1999 May;33(6):1646-54. doi: 10.1016/s0735-1097(99)00041-8.

DOI:10.1016/s0735-1097(99)00041-8

PMID:10334437

Abstract

OBJECTIVES

The purpose of this study was to assess the clinical feasibility of three-dimensional (3D) reconstruction of color Doppler signals in patients with mitral regurgitation.

BACKGROUND

Two-dimensional (2D) color Doppler has limited value in visualizing and quantifying asymmetric mitral regurgitation. Clinical studies on 3D reconstruction of Doppler signals in original color coding have not yet been performed in patients. We have developed a new procedure for 3D reconstruction of color Doppler.

METHODS

We studied 58 patients by transesophageal 3D echocardiography. The jet area was assessed by planimetry and the jet volumes by 3D Doppler. The regurgitant fractions, the volumes, and the angiographic degree of mitral regurgitation were assessed in 28 patients with central jets and compared with those of 30 patients with eccentric jets.

RESULTS

In all patients, jet areas and jet volumes significantly correlated with the angiographic grading (r = 0.73 and r = 0.90), the regurgitant fraction (r = 0.68 and r = 0.80) and the regurgitant volume (r = 0.66 and r = 0.90). In patients with central jets, significant correlations were found between jet area and angiography (r = 0.86), regurgitant fraction (r = 0.64) and regurgitant volume (r = 0.78). No significant correlations were found between jet area and angiography (r = 0.53), regurgitant fraction (r = 0.52) and regurgitant volume (r = 0.53) in the group of patients with eccentric jets. In contrast, jet volumes significantly correlated with angiography (r = 0.90), regurgitant fraction (r = 0.75) and regurgitant volume (r = 0.88) in the group of patients with eccentric jets.

CONCLUSIONS

Three-dimensional Doppler revealed new images of the complex jet geometry. In addition, jet volumes, assessed by an automated voxel count, independent of manual planimetry or subjective estimation, showed that 3D Doppler is also capable of quantifying asymmetric jets.

摘要

目的

本研究旨在评估二尖瓣反流患者彩色多普勒信号三维（3D）重建的临床可行性。

背景

二维（2D）彩色多普勒在可视化和量化不对称二尖瓣反流方面价值有限。尚未对患者进行原始颜色编码的多普勒信号三维重建的临床研究。我们已经开发出一种彩色多普勒三维重建的新方法。

方法

我们通过经食管三维超声心动图研究了58例患者。通过平面测量法评估射流面积，通过三维多普勒评估射流容积。在28例中心性射流患者中评估反流分数、容积和二尖瓣反流的血管造影分级，并与30例偏心性射流患者进行比较。

结果

在所有患者中，射流面积和射流容积与血管造影分级（r = 0.73和r = 0.90）、反流分数（r = 0.68和r = 0.80）以及反流容积（r = 0.66和r = 0.90）显著相关。在中心性射流患者中，射流面积与血管造影（r = 0.86）、反流分数（r = 0.64）和反流容积（r = 0.78）之间存在显著相关性。在偏心性射流患者组中，射流面积与血管造影（r = 0.53）、反流分数（r = 0.52）和反流容积（r = 0.53）之间未发现显著相关性。相比之下，在偏心性射流患者组中，射流容积与血管造影（r = 0.90）、反流分数（r = 0.75）和反流容积（r = 0.88）显著相关。