Lau G, Tan S Y, Chiang G, Poh W T
Department of Forensic Medicine, Institute of Science and Forensic Medicine, Singapore.
J Clin Pathol. 1998 Dec;51(12):931-4. doi: 10.1136/jcp.51.12.931.
An unusual case of metastatic bronchioloalveolar carcinoma of the lung presented as a pituitary tumour in a young adult Chinese female, who subsequently died after having undergone trans-sphenoidal resection. Metastatic cancers of the pituitary are uncommon even in necropsy series and rarely give rise to clinical symptoms. This case draws attention to the fact that, although uncommon, pituitary metastases have been noted with increasing frequency and their distinction from primary pituitary tumours is often difficult. A metastatic pituitary tumour may be the initial presentation of an unknown primary malignancy, wherein the metastatic deposits may also be limited to the pituitary gland. Clinicians and pathologists alike should consider a metastatic lesion in the differential diagnosis of a non-functioning pituitary tumour.
一名年轻中国女性的肺转移性细支气管肺泡癌表现为垂体肿瘤，这是一例不寻常的病例，该患者在接受经蝶窦切除术后死亡。即使在尸检系列中，垂体转移性癌也不常见，很少引起临床症状。该病例提醒人们注意，尽管垂体转移瘤不常见，但已观察到其发生率在增加，而且往往难以将其与原发性垂体肿瘤区分开来。转移性垂体肿瘤可能是未知原发性恶性肿瘤的首发表现，其中转移灶也可能仅限于垂体。临床医生和病理学家在对无功能垂体肿瘤进行鉴别诊断时均应考虑转移性病变。
