Krohn J
Department of Ophthalmology, University of Bergen, Norway.
Acta Ophthalmol Scand. 1999 Feb;77(1):9-12. doi: 10.1034/j.1600-0420.1999.770102.x.
Previous studies have indicated that there are preformed channels at the inner aspect of the anterior sclera, capable of draining fluid from the suprachoroidal space into scleral veins. The aim of this study was to characterize the cellular lining of these channels, and to compare it with the endothelium of Schlemm's canal, the collector channels and the scleral blood vessels.
Histological sections from the angular region of human eyes were prepared by an immunoperoxidase method to evaluate the expression of factor VIII-related antigen in different aqueous drainage channels.
The cellular lining of the scleral channels showed a weak immunostaining to factor VIII-related antigen. Factor VIII-related antigen was also detected in the endothelium of the collector channels and Schlemm's canal.
The positive immunoreaction to factor VIII-related antigen indicates that the previously described scleral channels, the collector channels and Schlemm's canal are all lined by an endothelium derived from a vascular origin.
以往研究表明，在前巩膜内侧存在预先形成的通道，能够将脉络膜上腔的液体引流至巩膜静脉。本研究的目的是对这些通道的细胞内衬进行特征描述，并将其与施莱姆管、集合管及巩膜血管的内皮进行比较。
采用免疫过氧化物酶法制备人眼角区的组织学切片，以评估不同房水引流通道中VIII因子相关抗原的表达。
巩膜通道的细胞内衬对VIII因子相关抗原呈弱阳性免疫染色。在集合管和施莱姆管的内皮中也检测到了VIII因子相关抗原。
对VIII因子相关抗原的阳性免疫反应表明，先前描述的巩膜通道、集合管和施莱姆管均由源自血管的内皮细胞衬里。
