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[恶性肿瘤生长过程中动物组织内的氧张力]

[Oxygen tension in the tissues of animals during the process of malignant tumor growth].

作者信息

Mosienko V S, Zagoruĭko L I

出版信息

Vopr Onkol. 1976;22(9):58-62.

PMID:1007140
Abstract

It has been shown polarographically that the oxygen supply and consumption in transplantable Heren carcinoma and normal tissues of the tumor organism are reduced as compared with such indices in intact animals. As the tumor grows, oxygen tension in normal tissues is gradually lowered both under normal conditions and oxygen ventilation, while the time of its consumption by tissues is longer. Such changes in tissues pO2 are not observed in subcutaneous transplantation of muscle tissue suspension in animals and also in transplantable tumor resorption.

摘要

极谱分析表明,与完整动物相比,可移植性赫伦癌及其机体正常组织中的氧气供应和消耗减少。随着肿瘤生长,正常组织中的氧分压在正常条件和氧通气情况下均逐渐降低,而组织消耗氧的时间延长。在动物皮下移植肌肉组织悬液以及可移植性肿瘤吸收过程中,未观察到组织pO2的此类变化。

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