Shimizu K, Hara K, Yatabe Y
Department of Medicine, Nagoya City Higashi General Hospital, Nagoya, Japan.
Int J Hematol. 1999 Feb;69(2):96-100.
A patient who developed Hodgkin's disease after an 11-year remission of marginal zone B-cell (MZB) lymphoma (low grade B-cell lymphoma of mucosa-associated lymphoid tissue type) is presented. Except for L26/CD20 expression by Reed-Sternberg cells, morphologic, immunophenotypic, and genotypic findings were compatible with the diagnosis of Hodgkin's disease. The relationship between Hodgkin's disease and the preceding MZB lymphoma in this patient is discussed.
本文报告1例在边缘区B细胞(MZB)淋巴瘤(黏膜相关淋巴组织型低度B细胞淋巴瘤)缓解11年后发生霍奇金淋巴瘤的患者。除里德-斯腾伯格细胞表达L26/CD20外,形态学、免疫表型和基因分型结果均符合霍奇金淋巴瘤的诊断。本文讨论了该患者霍奇金淋巴瘤与之前MZB淋巴瘤之间的关系。