McGoveran B M, Davis A M, Gross A E, Bell R S
University of Toronto, Ont.
Can J Surg. 1999 Feb;42(1):37-45.
To evaluate clinical and functional outcomes resulting from the allograft-composite technique used for proximal femoral osteoarticular reconstruction in patients who had limb salvage surgery for primary bone tumours.
A retrospective review of a prospectively gathered database to provide a descriptive study.
A tertiary care musculoskeletal oncology unit in a university hospital.
Patients treated between 1987 and 1993 were eligible for inclusion in this study if they met the following criteria: they were treated surgically for a primary malignant bone tumour; and a proximal femoral allograft-implant composite technique was used for the reconstruction.
Major postoperative complications with emphasis on mechanical complications in the reconstructive composite implant. Functional outcome in a subset of patients using the 1987 and 1994 versions of the Musculoskeletal Tumor Society instrument, the Short-Form-36 and the Toronto Extremity Salvage Score.
There were 5 mechanical and 2 infectious complications requiring surgical intervention. Functional scores were generally low.
Our results suggest that the perceived benefits of the composite technique may accrue only to a few patients, partly owing to the risk of mechanical complications. Although these can be reduced by avoiding the use of cement in the host femur, the generally poor functional outcomes suggest that this technique needs to be studied further in this group of patients and compared with other reconstructive techniques, particularly the prosthetic implant.
评估在接受保肢手术治疗原发性骨肿瘤的患者中,采用同种异体骨复合技术进行股骨近端骨关节重建所产生的临床和功能结果。
对前瞻性收集的数据库进行回顾性分析,以进行描述性研究。
大学医院的三级肌肉骨骼肿瘤治疗科室。
1987年至1993年间接受治疗的患者,若符合以下标准则纳入本研究:因原发性恶性骨肿瘤接受手术治疗;采用股骨近端同种异体骨-植入物复合技术进行重建。
术后主要并发症,重点关注重建复合植入物的机械并发症。部分患者使用1987年和1994年版的肌肉骨骼肿瘤学会工具、简短健康调查问卷(Short-Form-36)和多伦多肢体挽救评分进行功能评估。
有5例机械并发症和2例感染并发症需要手术干预。功能评分普遍较低。
我们的结果表明,复合技术的预期益处可能仅惠及少数患者,部分原因是存在机械并发症风险。虽然可以通过避免在宿主股骨中使用骨水泥来降低这些风险,但总体较差的功能结果表明,该技术需要在这组患者中进一步研究,并与其他重建技术,特别是假体植入物进行比较。