Müller-Hülsbeck S, Schwarzenberg H, Tschach T, Grimm J, Heller M
Klinik für Radiologische Diagnostik der Christian-Albrechts-Universität zu Kiel.
Rofo. 1999 Jan;170(1):94-8. doi: 10.1055/s-2007-1011014.
In vitro comparison of the 6F and 8F Amplatz thrombectomy device (ATD) for treatment of thrombotically occluded vessels in a flow-model.
Thrombectomy of clots from porcine blood was performed with either a 6F or an 8F Amplatz thrombectomy device (ATD) in a flow-model simulating a superficial femoral artery circuit (n = 40; 7.5 g: 7 mm diameter; 4.5 g: 5 mm diameter). Emboli caused during thrombectomy were determined in a three-step filter array (10 microns-1000 microns).
Thrombectomy was successful in all cases. In 5 mm/7 mm lumen time for thrombectomy was measured from 47 s/56s (8F) to 86 s/107 s (p < 0.01) (6F). Remaining thrombus weighted in 5 mm/7 mm lumen 0.04 g/-0.02 g (8F) and 0.05 g/-0.02 g (6F). Overall weight emboli determined for 1000 microns, 100 microns and 10 microns size and percentage of emboli related to original thrombus weight measured 0.23 g/4.96% (8F, 5 mm), 0.2 g/4.36% (6F, 5 mm), 0.08 g/1.13% (8F, 7 mm). and 0.09 g/1.18% (6F, 7 mm).
In vitro, the 6F ATD is in "vessels" with 5 mm and 7 mm diameter as effective as the 8F version. Particle embolization in flow-circuit was similar with both devices, although the 6F ATD requires a longer time for thrombectomy in vessel with larger diameter.
在血流模型中对6F和8F安普拉斯血栓切除术器械（ATD）治疗血栓闭塞血管进行体外比较。
在模拟股浅动脉循环的血流模型中，使用6F或8F安普拉斯血栓切除术器械（ATD）对猪血中的血栓进行清除（n = 40；7.5 g：直径7 mm；4.5 g：直径5 mm）。在一个三步过滤阵列（10微米 - 1000微米）中确定血栓切除过程中产生的栓子。
所有病例血栓切除均成功。在5 mm/7 mm管腔中，血栓切除时间从47秒/56秒（8F）到86秒/107秒（p < 0.01）（6F）。在5 mm/7 mm管腔中剩余血栓重量为0.04 g/-0.02 g（8F）和0.05 g/-0.02 g（6F）。针对1000微米、100微米和10微米尺寸确定的栓子总重量以及与原始血栓重量相关的栓子百分比分别为0.23 g/4.96%（8F，5 mm）、0.2 g/4.36%（6F，5 mm）、0.08 g/1.13%（8F，7 mm）和0.09 g/1.18%（6F，7 mm）。
在体外，6F ATD在直径为5 mm和7 mm的“血管”中与8F型号一样有效。两种器械在血流回路中的颗粒栓塞情况相似，尽管6F ATD在较大直径血管中进行血栓切除需要更长时间。
