Müller-Hülsbeck S, Schwarzenberg H, Bangard C, Steffens J C, Heller M
Klinik für Radiologische Diagnostik, Christian-Albrechts-Universität zu Kiel.
Rofo. 1998 Feb;168(2):191-4. doi: 10.1055/s-2007-1015207.
To compare the efficacy of vacuum pump controlled aspiration thrombectomy (VPCAT) with the Amplatz thrombectomy device (ATD) for treatment of thrombotic occlusions.
In a flow-model a superficial femoral artery is simulated. VPCAT provides the connection either of an aspiration catheter (AC, 8 F) or a multipurpose catheter (MPC, 8 F) with a vacuum pump (-110 mbar underpressure). 7 day old porcine blood (n = 30; 7.4 g +/- 0.1g) was treated with AC and MPC (VPCAT technique) and with the ATD.
Complete thrombectomy was achieved with all techniques. Thrombectomy time was short for ATD (8.8 +/- 0.94 s; p < 0.01). MPC caused the least overall weight of emboli related to thrombus weight (5.14 0/100; p < 0.01). ATD caused the least embolisms at 1000 microns (3.27 mg; p < 0.05), and the most embolisms at 100 microns and at 10 microns (26.5 mg and 26.9 mg; p < 0.01). The aspirated volume of the MPC (33 +/- 17 ml) was half the volume of the AC (65 +/- 25 ml).
In-vitro, VPCAT proves to be an alternative procedure to ATD. The use of a wide lumen multipurpose catheter is advantageous. In vitro, embolism rates of all methods are sufficiently low.
比较真空泵控制的抽吸血栓切除术（VPCAT）与安普拉斯血栓切除术装置（ATD）治疗血栓闭塞的疗效。
在血流模型中模拟股浅动脉。VPCAT将抽吸导管（AC，8F）或多用途导管（MPC，8F）与真空泵（负压-110毫巴）相连。用AC和MPC（VPCAT技术）以及ATD处理7日龄猪的血液（n = 30；7.4克±0.1克）。
所有技术均实现了完全血栓清除。ATD的血栓清除时间较短（8.8±0.94秒；p < 0.01）。与血栓重量相关的栓子总重量，MPC导致的最少（5.14%；p < 0.01）。ATD在1000微米处导致的栓子最少（3.27毫克；p < 0.05），而在100微米和10微米处导致的栓子最多（26.5毫克和26.9毫克；p < 0.01）。MPC的抽吸量（33±17毫升）是AC抽吸量（65±25毫升）的一半。
在体外，VPCAT被证明是ATD的一种替代方法。使用宽腔多用途导管具有优势。在体外，所有方法的栓塞率都足够低。
