Relation of fibrinolytic potentiation by estrogen to coagulation pathway activation in postmenopausal women.
作者信息
Koh K K, Horne M K, Csako G, Waclawiw M A, Cannon R O
机构信息
Cardiology Branch and the Office of Biostatistics Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892-1650, USA.
出版信息
Am J Cardiol. 1999 Feb 1;83(3):466-9, A10. doi: 10.1016/s0002-9149(98)00891-1.
Abstract
To determine whether enhanced fibrinolysis is a primary effect of estrogen or is secondary to activation of coagulation, we measured hemostatic factors before and after conjugated equine estrogen 0.625 mg/day for 1 month in 9 postmenopausal women. We found that potentiation of fibrinolysis is a primary effect of conjugated equine estrogens at this commonly used dosage in healthy postmenopausal women.
摘要
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