Male O, Diem E
Wien Klin Wochenschr. 1976 Nov 12;88(21):700-6.
As a result of progress in the modern treatment of burns, systemic candidosis (CA), in the sense of "surviving mycoses", has become increasingly frequent. The site of entry is not usually the wound, but the intestinal tract, which becomes overgrown by the yeasts as a consequence of the requisite therapy with antibacterial antibiotics in high dosage. Passage of the organism into the circulation occurs by persorption. In view of the bad prognosis of systemic CA, it is essential to recognize its incipient development and counteract by timely prophylactic measures, primarily sterilization of the intestine. In a developed case os systemic CA, the chances of cure improve with rapidity of recognition of the infection and initiation of treatment. Early diagnosis of the infection is achieved by the regular quantitative determination of the organism in the faeces, in urine and blood, as well as in swabs of mucous membranes and the wounds and, above all, by serological examination (movement of titre). The practical problems of the disease are demonstrated and discussed on the basis of 2 cases treated in this department.
由于现代烧伤治疗技术的进步，从“存活的真菌病”角度来看，系统性念珠菌病（CA）越来越常见。感染的入口通常不是伤口，而是肠道，由于必须使用高剂量的抗菌抗生素进行治疗，肠道会被酵母菌过度生长。病原体通过渗透进入循环系统。鉴于系统性CA的预后不良，必须认识到其早期发展并通过及时的预防措施进行对抗，主要是肠道消毒。在系统性CA的已发病例中，治愈的机会随着感染的快速识别和治疗的开始而增加。通过定期定量测定粪便、尿液、血液以及粘膜和伤口拭子中的病原体，尤其是通过血清学检查（滴度变化）来实现感染的早期诊断。基于本科室治疗的2例病例展示并讨论了该疾病的实际问题。
