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肝血虚证病理生理基础的初步研究

[Preliminary study on pathophysiological basis of liver-blood deficiency syndrome].

作者信息

Shi L, Zhang Z, Chen G

机构信息

Institute of Integrated TCM and Western Medicine, Hunan Medical University, Changsha.

出版信息

Hunan Yi Ke Da Xue Xue Bao. 1997;22(5):411-5.

Abstract

By ways of HPLC and RIA, multiple laboratory parameters were determined simultaneously in 84 patients of iron--deficiency anemia (IDA) or chronic aplastic anemia (CAA) with Liver-Blood Deficiency Syndrome (LBDS) diagnosed by differentiation of TCM. The results showed that LBDS had some pathophysiological characteristics such as decreased function of sympathicus and adrenal medulla axis, increasing of L-EK, lower energy metabolism of erythrocyte, lower rate of body metabolism, sodium and water imbalance, and abnormalities in hemorrheology and erythrocyte deformability. It is suggested that the patients with LBDS are in a state of protective compensation in blood volume regulation.

摘要

采用高效液相色谱法(HPLC)和放射免疫分析法(RIA),对84例经中医辨证诊断为缺铁性贫血(IDA)或慢性再生障碍性贫血(CAA)且伴有肝血不足证(LBDS)的患者同时测定多项实验室指标。结果显示,肝血不足证具有一些病理生理特征,如交感神经和肾上腺髓质轴功能减退、白细胞介素 - 促红细胞生成素(L - EK)升高、红细胞能量代谢降低、机体代谢率降低、钠水失衡以及血液流变学和红细胞变形性异常。提示肝血不足证患者在血容量调节方面处于保护性代偿状态。

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