Chen C H, Shi L J, Shu Y G
Institute of Combined Traditional Chinese and Western Medicines, Xiangya Hospital, Central South University, Changsha 410008, China.
Hunan Yi Ke Da Xue Xue Bao. 2001 Aug 28;26(4):337-9.
Using HPLC-ED or RIA, we determined simultaneously 15 indexes in 27 patients with the liver-blood deficiency syndrome (LDBD). By means of multivarivate hierarchical cluster analysis and selections of typical variate, the results showed that 15 indexes were classified into 5 groups, and the typical variates of each groups were NE, T3, TXB2, ALD and cGMP. It suggests that LBDS has some pathopysiological characteristics such as decreased functions of sympathetic nerve activation, lower T3 syndrome, imbalance of the active substance regulating cardiovascular function and metabolism of salt and water, and abnormalities second signal substance in cellular membrane.
我们使用高效液相色谱-电化学检测法(HPLC-ED)或放射免疫分析法(RIA),同时测定了27例肝血不足证患者的15项指标。通过多变量层次聚类分析和典型变量选择,结果显示15项指标分为5组,每组的典型变量为去甲肾上腺素(NE)、三碘甲状腺原氨酸(T3)、血栓素B2(TXB2)、醛固酮(ALD)和环磷酸鸟苷(cGMP)。提示肝血不足证具有交感神经激活功能降低、低T3综合征、心血管功能及水盐代谢活性物质失衡、细胞膜第二信号物质异常等病理生理特征。