Cabadés A, Echanove I, Cebrián J, Cardona J, Valls F, Parra V, Bertomeu V, Francés M, González E, Ballenilla F, Sogorb F, Rodríguez R, Mota A, Guardiola F, Calabuig J
Rev Esp Cardiol. 1999 Feb;52(2):123-33. doi: 10.1016/s0300-8932(99)74880-3.
Regional registers of patients with acute myocardial infarction are scarce in Spain. The PRIMVAC register (Proyecto de Registro de Infarto agudo de Miocardio de Valencia, Alicante y Castellón) was initiated to obtain updated information on the management of these patients in the Valencia Autonomous Community. Data of the first twelve months of the register are presented.
The 17 participating hospitals cover 2,833,938 inhabitants. Demographic, clinical, procedural and outcome data as well as predictive variables of mortality were analysed in the patients with acute myocardial infarction during their stay in the coronary care units from 1 December 1994 to 30 November 1995.
During 12 months, 2,377 patients were included. Mean age was 65.3 years (SD 11.9) and 23.2% were female. Left ventricular failure was present in 39.8%. Thrombolytic therapy was applied in 42.1% with a median time delay of 195 min from chest pain onset. This time was longer in the women (250 min) and in the elderly (210 min). The in-coronary-care-unit-mortality rate was 13.9%. Age, female gender, diabetes, previous myocardial infarction, Q wave and right ventricular infarction independently predicted increased early mortality.
Present data show the feasibility of an acute myocardial infarction register in the Valencia Autonomous Community. Although an acceptable level of thrombolysis has been reached, the mortality rate is still high. The long delay in initiating thrombolysis, particularly in female and elderly patients is remarkable.
在西班牙,急性心肌梗死患者的区域登记册非常稀少。启动PRIMVAC登记册(巴伦西亚、阿利坎特和卡斯特利翁急性心肌梗死登记项目)是为了获取巴伦西亚自治区这些患者管理方面的最新信息。本文展示了该登记册前十二个月的数据。
17家参与医院覆盖2833938名居民。对1994年12月1日至1995年11月30日期间在冠心病监护病房住院的急性心肌梗死患者的人口统计学、临床、治疗过程及结局数据,以及死亡率预测变量进行了分析。
在12个月期间,纳入了2377例患者。平均年龄为65.3岁(标准差11.9),女性占23.2%。39.8%的患者存在左心室衰竭。42.1%的患者接受了溶栓治疗,从胸痛发作到溶栓的中位时间延迟为195分钟。女性(250分钟)和老年人(210分钟)的这一延迟时间更长。冠心病监护病房内的死亡率为13.9%。年龄、女性、糖尿病、既往心肌梗死、Q波和右心室梗死独立预测早期死亡率增加。
目前的数据表明在巴伦西亚自治区建立急性心肌梗死登记册是可行的。虽然已达到可接受的溶栓水平,但死亡率仍然很高。溶栓启动延迟时间长,尤其是女性和老年患者,这一点很显著。