Young I H, Crockett A J, McDonald C F
Department of Respiratory Medicine, Royal Prince Alfred Hospital, Sydney.
N Z Med J. 1999 Jan 22;112(1080):15-8.
Evidence shows that patients with chronic obstructive pulmonary disease and a stable daytime PaO2 of 55 mm Hg or less will have longer life expectancy if given supplemental oxygen to keep the PaO2 above 60 mm Hg, preferably for longer than 15 hours a day, including sleep. There is some evidence for improved quality of life. It is reasonable to offer this therapy for other lung diseases which cause chronic hypoxaemia, and there are also less well defined indications for supplemental oxygen during exercise, sleep and air travel.
有证据表明，对于慢性阻塞性肺疾病患者，若其日间动脉血氧分压（PaO2）稳定在55毫米汞柱及以下，给予补充氧气使PaO2维持在60毫米汞柱以上，最好每天吸氧超过15小时，包括睡眠期间，其预期寿命会更长。有一些证据表明生活质量会得到改善。对于其他导致慢性低氧血症的肺部疾病，提供这种治疗是合理的，而且在运动、睡眠和航空旅行期间补充氧气的适应证也不太明确。
