Busse W W
University of Wisconsin, Madison, USA.
J Clin Pharmacol. 1999 Mar;39(3):241-5.
It has long been known that patients with viral respiratory infections develop temporary asthma-like symptoms or see a worsening of their existing asthmatic symptoms or develop full-blown asthma during the infection. It should not be surprising, in view of this observation, that these same viruses have been found to initiate the same inflammatory processes as seen and characterized in the asthmatic patient. This has clear implications for therapy of asthmatic patients.
长期以来,人们一直知道病毒性呼吸道感染患者会出现暂时的哮喘样症状,或者其现有的哮喘症状会加重,或者在感染期间发展为全面的哮喘。鉴于这一观察结果,这些相同的病毒被发现会引发与哮喘患者中所见及特征相同的炎症过程,这并不令人惊讶。这对哮喘患者的治疗具有明确的意义。